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PrimaS is a new multimodal chromatography ligand that combines elements of hydrogen bonding with anion exchange chromatography.
It offers unique selectivities in many important product areas.
It supports purification of single-stranded RNA at ambient temperature and also fractionates ssRNA by size.
For best results, combine PrimaS with a capture or polishing column from our mRNA purification toolbox.
Affinity, hydrophobic interaction and revserse phase options. All technologies are easily scalable from lab to manufacturing, and will ensure removal of process and product impurities, including endotoxin, double stranded species, and fragments.
A complete downstream workflow from pDNA to mRNA.
 
In vitro transcription requires sufficient quantities of high quality pDNA. Start your production with the HiP2 Plasmid Process Pack – a complete downstream solution for highly homogeneous pDNA.
Coming soon.

Keep an eye out for more – improving our current industry-leading separation of empty and full AAV capsids, and up to 5.5 log removal of endotoxin from bacteriophages and products produced in mamalian cell culture. All this, coming soon as an application for PrimaS.
Elevate your separation capabilities with PrimaS!
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